Urine Drug Screen, False-Positive

Opiates

  • Poppy seeds
  • Rifampin
  • Quinine
  • Quinolone antibiotic
  • Diphenhydramine
  • Kadian: In very high doses could cause false positive for Hydromorphone

Cocaine

  • Amoxicillin
  • Tonic water

Amphetamine/Methamphetamaine

  • Chlorpromazine
  • Desipramine
  • Ephedrine
  • Fluoxetine
  • Labetolol
  • Phenylephrine
  • Promethazine
  • Pseudoephedrine
  • Ranitidine
  • Trazodone
  • Vicks inhalers
  • Wellbutrin

Benzodiazepines

  • Sertraline (Zoloft)
  • Iboprofen
  • Naproxen

Cannabinoids

  • Naproxen
  • Piroxicam
  • Proton Pump Inhibitors
  • Tolmetin
  • Dronabinol
  • Pantoprazole

References

  • Brahm N, Yeager L, Fox M, et al. Commonly prescribed medications and potential false-positive urine drug screens. Am J Health-Syst Pharm. 2010;67:1344-50.
  • Nasky KM, Cowan GL, Knittel DR. False-positive urine screening for benzodiazepines: an association with sertraline? A two-year retrospective chart analysis. Psychiatry. 2009; 6:36-9.
  • Woelfel JA. Drug abuse urine tests: false-positive results. Pharmacist’s Letter/Prescriber’s Letter. 2005;21(3):210314.
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